Synonyms of backbonenext
1
2
: something that resembles a backbone: such as
a
: a chief mountain ridge, range, or system
b
: the foundation or most substantial or sturdiest part of something
c
: the longest chain of atoms or groups of atoms in a usually long molecule (such as a polymer or protein)
d
: the primary high-speed hardware and transmission lines of a telecommunications network (such as the Internet)
3
: firm and resolute character
4

Synonyms of backbone

Examples of backbone in a Sentence

She is the backbone of the family. He showed some backbone by refusing to compromise his values.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The tablet combines bictegravir, the backbone of Gilead’s blockbuster HIV pill Biktarvy, with lenacapavir, a first-in-class capsid inhibitor that has become a centerpiece of the company’s long-term strategy for HIV treatment and prevention. Justina Lee, CNBC, 28 Aug. 2026 Combine drought with fire and the backbone of the Everglades — its marshy peat soil — also becomes more vulnerable. Jenny Staletovich, Miami Herald, 27 Aug. 2026 Ukraine has also targeted oil facilities that are the backbone of the economy in Russia, which is one of the world’s largest energy producers. ABC News, 26 Aug. 2026 Medical records often become the backbone of a workers’ compensation claim under the official guidelines of the Kentucky Department of Workers’ Claims. Jason Phillips, Ascend Agency, 24 Aug. 2026 See All Example Sentences for backbone

Word History

First Known Use

14th century, in the meaning defined at sense 1

Time Traveler
The first known use of backbone was in the 14th century

Browse Nearby Words

Cite this Entry

“Backbone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/backbone. Accessed 1 Sep. 2026.

Kids Definition

backbone

noun
1
: the skeleton of the trunk and tail of a vertebrate that consists of a jointed series of vertebrae enclosing and protecting the spinal cord

called also spinal column

2
: the foundation or sturdiest part of something
3
: firmness of character
a coward with no backbone
backboned adjective

Medical Definition

1
2
: the longest chain of atoms or groups of atoms in a usually long molecule (as a polymer or protein)

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