1
: the flowing blood in a circulatory system
2
: a mainstream of power or vitality
… introduce into the economic bloodstream a large amount of money …Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The liver breaks down various forms of vitamin K into metabolites, which are released into the bloodstream. Ayesha Gulzar, Verywell Health, 31 Aug. 2026 For the first time, Gallup asked about consumption of nicotine pouches, small sachets placed between the upper lip and gum that allow direct absorption of nicotine into the bloodstream. Dario Sabaghi, Forbes.com, 29 Aug. 2026 For example, when the medication is taken as directed, under the tongue or inside the cheek, relatively little naloxone reaches the bloodstream. Encyclopedia Britannica, 28 Aug. 2026 Dolly once said a return to roots kept her sane, and appreciation for music that felt like her bloodstream moved her deeply. Martha Ackmann, Vulture, 27 Aug. 2026 See All Example Sentences for bloodstream

Word History

First Known Use

13th century, in the meaning defined at sense 1

Time Traveler
The first known use of bloodstream was in the 13th century

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Cite this Entry

“Bloodstream.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/bloodstream. Accessed 1 Sep. 2026.

Kids Definition

bloodstream

noun
: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun
: the flowing blood in a circulatory system
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