high-grade

adjective

ˈhī-ˈgrād How to pronounce high-grade (audio)
Synonyms of high-gradenext
1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Low-grade astrocytomas are more common in children, while high-grade astrocytomas, such as glioblastoma, tend to grow and spread within the brain and spinal cord quickly and are more common in adults. — Angeline Jane Bernabe, ABC News, 28 Aug. 2026 The swivel is made of high-grade metal, and the bag is made with super durable Maya hide leather. — Bestreviews, Chicago Tribune, 18 Aug. 2026 Amid ongoing concerns, district officials have assured parents schools are safe, campuses have been sanitized and high-grade air filters installed. — Howard Blume, Los Angeles Times, 12 Aug. 2026 Most of it is bigeye and yellowfin tuna, which is sold fresh as high-grade fish used in poke and sushi. — NPR, 3 Aug. 2026 See All Example Sentences for high-grade

Word History

First Known Use

1826, in the meaning defined at sense 1

Time Traveler
The first known use of high-grade was in 1826

Rhymes for high-grade

See All Rhymes for high-grade

Browse Nearby Words

High German consonant shift
high-grade
high-grading
See all Nearby Words

Cite this Entry

“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 1 Sep. 2026.

Copy Citation

Kids Definition

high-grade

adjective
ˈhī-ˈgrād
: of a better grade or quality

Medical Definition

high-grade

adjective
ˈhī-ˈgrād How to pronounce high-grade (audio)
: being near the upper, most serious, or most life-threatening extreme of a specified range
high-grade gliomas
high-grade cervical dysplasia
compare low-grade

More from Merriam-Webster on high-grade

Thesaurus: All synonyms and antonyms for high-grade

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