: an interleukin that is produced by various cells (such as macrophages, fibroblasts, T cells, and tumor cells) and that induces the maturation of B cells and growth of myeloma cells, activates and induces the proliferation of T cells, stimulates synthesis of plasma proteins (such as fibrinogen), and plays a role in producing fever
Last year, researchers discovered that older women who were socially active had lower levels of interleukin-6, a substance linked to chronic inflammation that is found at high levels in people with Alzheimer's disease, heart disease, and cancer.Andrew Weil
abbreviation IL-6

Examples of interleukin-6 in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Pacibekitug is an antibody that targets IL-6, or interleukin-6, a protein involved in regulating immune responses. Andrew Joseph, STAT, 29 Aug. 2026 Turmeric and Black Pepper Turmeric’s active ingredient, curcumin, is an antioxidant that may lower inflammatory markers like C-reactive protein and interleukin-6. Sarah Anzlovar, Verywell Health, 4 Aug. 2026 People with detectable plastic particles also had higher levels of inflammatory markers in coronary blood, including interleukin-6 and tumor necrosis factor-alpha. Tom Gavin, EverydayHealth.com, 15 July 2026 Several multinational clinical trials are underway to test the effects of inhibitors of interleukin-6, another of the immune system’s chemical messengers, on heart disease outcomes. Melinda Wenner Moyer, Scientific American, 14 Apr. 2026 See All Example Sentences for interleukin-6

Word History

First Known Use

1987, in the meaning defined above

Time Traveler
The first known use of interleukin-6 was in 1987

Browse Nearby Words

Cite this Entry

“Interleukin-6.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/interleukin-6. Accessed 1 Sep. 2026.

Medical Definition

: an interleukin that is produced by various cells (as macrophages, fibroblasts, T cells, and tumor cells) and that acts as a pyrogen, induces maturation of B cells and growth of myeloma cells, activates and induces proliferation of T cells, and stimulates synthesis of plasma proteins (as fibrinogen)
abbreviation IL-6
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!