1
2
: the base on which an organism lives
the soil is the substrate of most seed plants
3
: a substance acted upon (as by an enzyme)

Did you know?

With its Latin prefix sub-, "below", substrate obviously refers to a layer under something else. Rock may serve as the substrate for the coral in a coral reef. Tiny wafers of silicon (or another semiconductor) serve as the substrate for computer chips. Substrate may also mean subsoil—that is, the layer under the topsoil, lacking in organic matter or humus. Substrate is part of the vocabulary of various other sciences, including chemistry and biology. But although it's mostly a scientific term, writers may also use it to mean simply "foundation"—for instance, when observing that reading is the substrate on which most other learning is based.

Examples of substrate in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Saturated in velvety blues, reds, and blacks, Zumthor’s surfaces all but vibrate; the subtle variations in the application of the paint and the alchemy of the pigment on the concrete substrate bring the walls maximally to life. Katy Barkan, Artforum, 1 Sep. 2026 The GaN-on-silicon structure used by the team restricted the maximum breakdown voltage, meaning different substrates could potentially allow the devices to go even higher. Rupendra Brahambhatt, Interesting Engineering, 30 Aug. 2026 Selecting the appropriate one for changing season conditions can further complicate matters when cooler nights create colder ground, and without the right sleeping pad, that cooler substrate beneath you can translate to a cooler night’s sleep. Clay Abney, Travel + Leisure, 27 Aug. 2026 Although considerable research has focused on removing dyes from wastewater, comparatively less has addressed removing them directly from textile substrates, according to the researchers. Alexandra Harrell, Footwear News, 26 Aug. 2026 See All Example Sentences for substrate

Word History

Etymology

Medieval Latin substratum

First Known Use

1730, in the meaning defined at sense 1

Time Traveler
The first known use of substrate was in 1730

Browse Nearby Words

Cite this Entry

“Substrate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/substrate. Accessed 4 Sep. 2026.

Kids Definition

1
: an underlying layer: as
b
: the base on which an organism lives or over which it moves
the soil is the substrate of most plants
2
: a substance acted upon (as by an enzyme)

Medical Definition

1
2
: the base on which an organism lives
3
: a substance acted upon (as by an enzyme)
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