annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
Recent Examples on the Web
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The key will be whether a stronger supporting cast and a more run-heavy system helps Mendoza’s replacement, Josh Hoover, to cut down on the turnovers that vexed him at TCU.—
Michael Marot,
Chicago Tribune,
31 Aug. 2026 Garcia and fellow Democrats are mindful of what’s driving unhappy voters who face a vexing mix of inflation and weak economic growth.—Los Angeles Times,
27 Aug. 2026 Over time, a group of shareholders became particularly vexed with Taj Hotels, which had managed the property since 2005.—
Noah Shachtman,
Vanity Fair,
25 Aug. 2026 Zinn in the years to come was vexed both morally and politically by the impersonality of the killing as a bombardier.—Literary Hub,
12 Aug. 2026 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way